Recombinant CD147 antibody

Catalog No. ABIN7072342

This Mouse Monoclonal antibody specifically detects CD147 in ELISA and BR. It exhibits reactivity toward Human.

Quick Overview for Recombinant CD147 antibody (ABIN7072342)

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD147 antibody is un-conjugated

Application: ELISA, Blocking Reagent (BR)

Clone: Ab-1

Product Details anti-CD147 Antibody

Purpose: Anti-Basigin [Ab-1], Mouse IgG1, kappa

Specificity: The antibody binds to basigin with an affinity (Kd) of 4 nM reported for the original antibody.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogen: Recombinant ectodomains of human basigin.

Isotype: IgG1 kappa

Application Details

Application Notes: The antibody binds specifically to basigin, a protein of the immunoglobulin superfamily which is expressed on the surface of erythrocyte and acts as a receptor for the human malaria parasite P. falciparum. The recombinant chimeric monoclonal antibody Ab-1 acts by blocking the interaction between basigin and PfRH5, a ligand necessary for the P. falciparum erythrocyte invasion, thereby inhibiting the development of malaria.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for CD147

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Alternative Name: Basigin

Background: CD147, BSG, Cluster of differentiation 147, Extracellular matrix metalloproteinase inducer, EMMPRIN, 5F7, Collagenase stimulatory factor, Leukocyte activation antigen M6, Tumor cell-derived collagenase stimulatory factor, TCSF

UniProt: P35613

Pathways: S100 Proteins