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Recombinant L-Selectin antibody

This anti-L-Selectin antibody is a Rabbit Chimeric antibody detecting L-Selectin in FACS, IHC, IP and BR. Suitable for Mouse.
Catalog No. ABIN7072347

Quick Overview for Recombinant L-Selectin antibody (ABIN7072347)

Target

See all L-Selectin (SELL) Antibodies
L-Selectin (SELL) (Selectin L (SELL))

Antibody Type

Recombinant Antibody

Reactivity

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Mouse

Host

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Rabbit

Clonality

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Chimeric

Conjugate

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This L-Selectin antibody is un-conjugated

Application

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Blocking Reagent (BR)

Clone

MEL-14
  • Purpose

    Anti-CD62L [MEL-14], Rabbit IgG, kappa

    Specificity

    This antibody binds to mouse CD62L the mouse peripheral lymph node homing receptor, which is a lectin-like cell surface protein rapidly down-regulated upon cell activation with phorbol 12-myristate 13-acetate.

    Characteristics

    Original Species of Ab: Rat

    Original Format of Ab: IgG2a

    Purification

    Protein A affinity purified

    Immunogen

    C3H/eb mouse B lymphoma 38C-13.

    Isotype

    IgG kappa
  • Application Notes

    This antibody detects mouse CD62L and has been reported to inhibit the interaction of neutrophils with endothelial cells in vitro and inhibit the migration of neutrophils from the blood into sites of acute inflammation in the skin (Lewinsohn et al. 1987).

    Comment

    This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target

    L-Selectin (SELL) (Selectin L (SELL))

    Alternative Name

    CD62L

    Background

    L-selectin, LECAM-1, Ly-22, MEL14, Leu-8

    UniProt

    P18337
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