Recombinant ISR-alpha antibody

Catalog No. ABIN7072386

This anti-ISR-alpha antibody is a Rabbit Chimeric antibody detecting ISR-alpha in Crys. Suitable for Human.

Quick Overview for Recombinant ISR-alpha antibody (ABIN7072386)

Target: ISR-alpha (Insulin Receptor alpha (ISR-alpha))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This ISR-alpha antibody is un-conjugated

Application: Crystallization (Crys)

Clone: Fab 83-7

Product Details anti-ISR-alpha Antibody

Purpose: Anti-Insulin receptor alpha [Fab 83-7], Rabbit IgG, kappa

Specificity: This antibody recognizes an epitope within the cysteine rich region (amino acids 140-301) of the extracellular domain of the human insulin receptor alpha.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogen: This antibody was raised by immunizing mice with IM-9 lymphocytes followed by purified insulin receptor.

Isotype: IgG kappa

Application Details

Application Notes: This antibody forms a stable complex with the L1-CR fragment of the human insulin receptor alpha-subunit. Consequently, this antibody can be used to facilitate the crystallization of the complex, and the establishment of its structure (McKern et al, 2006).

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for ISR-alpha

Target: ISR-alpha (Insulin Receptor alpha (ISR-alpha))

Alternative Name: Insulin receptor alpha

Background: CD220

UniProt: P06213