Recombinant Glycophorin A M Antigen antibody

Catalog No. ABIN7072402

This Rabbit Chimeric antibody specifically detects Glycophorin A M Antigen in ELISA, InhA and WB. It exhibits reactivity toward Human.

Quick Overview for Recombinant Glycophorin A M Antigen antibody (ABIN7072402)

Target: Glycophorin A M Antigen

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: Un-conjugated

Application: ELISA, Inhibition Assay (InhA), Western Blotting (WB)

Clone: M2A1

Product Details

Purpose: Anti-Glycophorin A M antigen [M2A1], Rabbit IgG, kappa

Specificity: M2A1 binds specifically to the M antigen on human erythrocytes, and shows no reactivity to N antigen. The epitope for this antibody includes the amino-terminal serine residue and sialic acid residues of glycophorin A. The reactivity of M2A1 for M antigen is pH - and salt-dependent (optimum ~ pH 8-9). Blood group antigen M is located on the major sialoglycoprotein (glycophorin A) of red blood cells.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogen: M2A1 was prepared by immunzing BALB/c mice with human red blood cells of the M phenotype, and was screened by testing for anti-M activity.

Isotype: IgG kappa

Application Details

Application Notes: M2A1 can bind to M antigen of glycophorin A and can be used in ELISAs, immunoblots and modified M glycoprotein can be used for inhibition tests.

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details

Target: Glycophorin A M Antigen

Background: CD235a, M sialoglycoprotein, PAS-2

UniProt: P02724