Recombinant ICOSLG antibody
Quick Overview for Recombinant ICOSLG antibody (ABIN7072430)
Target
See all ICOSLG AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-ICOSL [HK5.3], Rabbit IgG, kappa
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Specificity
- This antibody specifically binds to mouse ICOSL and competes with binding of ICOS.
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Characteristics
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Original Species of Ab: Rat
Original Format of Ab: IgG2a
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Purification
- Protein A affinity purified
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Immunogen
- This antibody was raised by immunizing SD rat with mouse B7h-transfected L cells and fusing immune splenocytes with P3U1 myeloma cells and screened for binding to mouse B7h-transfected NRK cells.
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Isotype
- IgG kappa
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anti-Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 23-249) antibody
ICOSLG Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 23-149) antibodyICOSLG Reactivity: Human WB, ELISA, IHC, FACS, IF, Coat, StM Host: Mouse Monoclonal ICOSL-3111 unconjugated
anti-Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 19-256) antibodyICOSLG Reactivity: Human ELISA, FACS Host: Mouse Monoclonal 1G6E1 unconjugated
anti-Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 58-249) antibodyICOSLG Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 19-256) antibodyICOSLG Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 197-246) antibodyICOSLG Reactivity: Human WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 23-149) antibodyICOSLG Reactivity: Human ELISA, IHC, Coat, StM, ISt Host: Mouse Monoclonal ICOSL-3260 unconjugated
anti-Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 19-256) antibodyICOSLG Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 19-120) antibodyICOSLG Reactivity: Human, Mouse WB, ELISA, FACS Host: Rabbit Polyclonal unconjugated
anti-Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (AA 19-256) antibodyICOSLG Reactivity: Human ELISA, FACS Host: Rabbit Monoclonal DM97 unconjugated
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Application Notes
- This antibody has been used to detect murine ICOSL by flow cytometry. It is able to block ICOSL interacting with ICOSL and inhibit T-cell proliferation in a collagen type II (CII)-induced arthritis model.
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Comment
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This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
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Alternative Name
- ICOSL
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Background
- B7RP-1, B7-related protein 1, ICOS ligand, CD275, LICOS, B7h
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UniProt
- Q9JHJ8
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Pathways
- Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
Target
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