Recombinant CD137 antibody
Quick Overview for Recombinant CD137 antibody (ABIN7072489)
Target
See all CD137 (TNFRSF9) AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-4-1BB [LOB12.3], Rabbit IgG, kappa
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Specificity
- This antibody binds to mouse 4-1BB (CD137).
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Characteristics
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Original Species of Ab: Rat
Original Format of Ab: IgG1
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Purification
- Protein A affinity purified
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Immunogen
- This antibody was generated by immunizing rats with recombinant CD137-Fc fusion protein.
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Isotype
- IgG kappa
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 101-200) antibody
TNFRSF9 Reactivity: Human, Mouse, Rat ELISA, WB, FACS, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 19-188) antibodyTNFRSF9 Reactivity: Human ELISA, WB, FACS, IHC, IF Host: Mouse Monoclonal 4-1BB-3201 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 214-255) antibodyTNFRSF9 Reactivity: Human ELISA, WB, FACS Host: Mouse Monoclonal 2A12C2 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 40-153) antibodyTNFRSF9 Reactivity: Human WB, FACS Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 150-250) antibodyTNFRSF9 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 24-186) antibodyTNFRSF9 Reactivity: Human ELISA, FACS Host: Rabbit Monoclonal DM66 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 24-186) antibodyTNFRSF9 Reactivity: Human ELISA, FACS Host: Mouse Monoclonal 4G10B9 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (Internal Region) antibodyTNFRSF9 Reactivity: Human, Rat ELISA, WB, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (Extracellular Domain) antibodyTNFRSF9 Reactivity: Human, Non-Human Primate ELISA, FACS, IP Host: Mouse Monoclonal 4B4-1 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (Extracellular Domain) antibodyTNFRSF9 Reactivity: Human, Non-Human Primate ELISA, FACS, Func, IP Host: Mouse Monoclonal 4B4-1 unconjugated
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Application Notes
- This antibody can be used to detect mouse 4-1BB (CD137). In its original rat IgG1 format, this antibody had agonistic effect and prolonged survival of mice bearing CT26 or A31 tumors. In the original publication another clone LOB12 disclosed which has a rat IgG2a isotype. This has led to some confusion in the literature with regards to the original isotype of LOB12 and LOB12.3. We offer this antibody in both formats as well as murine versions so that researchers may choose the isotype most appropriate for their assays.
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Comment
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This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
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Alternative Name
- 4-1BB
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Background
- CD137, TNFRSF9, 41BB, 4-1BBL Ligand, Tumor necrosis factor superfamily member 9, TNF receptor superfamily member 9, LOB 12.3, LOB123, LOB12.3
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UniProt
- P20334
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Pathways
- Cancer Immune Checkpoints
Target
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