Recombinant IL-9 antibody

Catalog No. ABIN7072551

This anti-IL-9 antibody is a Rabbit Chimeric antibody detecting IL-9 in FACS and BP. Suitable for Mouse.

Quick Overview for Recombinant IL-9 antibody (ABIN7072551)

Target: IL-9 (IL9) (Interleukin 9 (IL9))

Antibody Type: Recombinant Antibody

Reactivity: Mouse

Host: Rabbit

Clonality: Chimeric

Conjugate: This IL-9 antibody is un-conjugated

Application: Flow Cytometry (FACS), Blocking Peptide (BP)

Clone: D9302C12

Product Details anti-IL-9 Antibody

Purpose: Anti-IL-9 [D9302C12], Rabbit IgG, kappa

Specificity: This antibody is specific for murine IL-9.

Characteristics:

Original Species of Ab: Hamster, Armenian

Original Format of Ab: IgG

Purification: Protein A affinity purified

Immunogen: This antibody was raised by immunising Armenian hamsters with Baculovirus-expressed, recombinant murine IL-9.

Isotype: IgG kappa

Application Details

Application Notes: In vitro, this antibody has inhibitory effects on IL-9 bioactivity, and inhibits the differentiation of Th17 cells and consequent production of IL-17 (Li et al, 2010). This antibody is also able to neutralise IL-9 in vivo (Li et al, 2010). Administration of this antibody suppresses acute experimental autoimmune encephalomyelitis (EAE), with an observed reduction in MOG-specific Th1 and Th17 cells in the periphery and the CNS (Li et al, 2010).

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Hamster IgG2 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for IL-9

Target: IL-9 (IL9) (Interleukin 9 (IL9))

Alternative Name: IL-9

Background: Interleukin-9, IL9, Cytokine P40, T-cell growth factor P40

UniProt: P15247

Pathways: JAK-STAT Signaling