Recombinant Fc epsilon R (N-Term) antibody
Reactivity: Human
FACS, BR
Host: Rabbit
Chimeric
IB10
unconjugated
Recombinant Antibody
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- Target
- Fc epsilon R
- Antibody Type
- Recombinant Antibody
- Binding Specificity
- N-Term
- Reactivity
- Human
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Host
- Rabbit
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Clonality
- Chimeric
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Conjugate
- Un-conjugated
- Application
- Flow Cytometry (FACS), Blocking Reagent (BR)
- Purpose
- Anti-Fc epsilon R [IB10], Rabbit IgG, kappa
- Specificity
- This antibody binds to human Fc epsilon receptor and competes with IgE binding.
- Characteristics
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
- Purification
- Protein A affinity purified
- Immunogen
- Recombinant human protein, N-terminus.
- Clone
- IB10
- Isotype
- IgG kappa
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- Application Notes
- IB10 competes with IgE for binding to human FceRIa, consequently, its binding to mast cells and basophils is decreased when IgE concentration is high, but it does block IgE binding to these cells. IB10 and IE7 (Ab01397) do not crossblock each other's binding.
- Comment
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % Proclin 300.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- Fc epsilon R
- Background
- FceRI, IgE receptor
- UniProt
- P30273
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