Recombinant CD37 antibody

Catalog No. ABIN7072629

This anti-CD37 antibody is a Mouse Monoclonal antibody detecting CD37 in FACS, IF and IHC. Suitable for Human.

Quick Overview for Recombinant CD37 antibody (ABIN7072629)

Target: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD37 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)

Clone: IPO-24 (ZC37-24)

Product Details anti-CD37 Antibody

Purpose: Anti-CD37 [IPO-24 (ZC37-24)], Mouse IgG2b, kappa

Specificity: This antibody recognizes CD37, which is a cell surface protein, present mostly on mature B cells and B cell malignancies.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG2b

Purification: Protein A affinity purified

Immunogen: This antibody was raised by immunizing mice with spleen cells of a patient with hairy cell leukemia.

Isotype: IgG2b kappa

Application Details

Application Notes: This antibody is recommended for the analysis and detection of B cells and their malignancies as CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies, such as B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin's lymphoma (B-NHL). Consequently, this antibody might be useful for the treatment of B cell malignancies and autoimmune and inflammatory diseases that involve B cells in their pathology. Finally, IPO-24 antibody, might be used to identify CD37 via various techniques. For instance, it was used to evaluate CD37 expression in mantle cell lymphoma samples via immunohistochemistry (Leshchenko et al., 2010).

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for CD37

Target: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Alternative Name: CD37

Background: Tetraspanin-26, Leukocyte antigen CD37, tetraspanin, Tspan-26, Gp52-40

UniProt: P11049

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response