Recombinant PRMT5 antibody

Catalog No. ABIN7072696

This Rabbit Chimeric antibody specifically detects PRMT5 in ELISA, IF, ChIP and MS. It exhibits reactivity toward Human.

Quick Overview for Recombinant PRMT5 antibody (ABIN7072696)

Target: PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This PRMT5 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Mass Spectrometry (MS)

Clone: RAB-C136

Product Details anti-PRMT5 Antibody

Purpose: Anti-PRMT5 [RAB-C136], Rabbit IgG, kappa

Specificity: This antibody recognizes PRMT5 (Protein arginine N-methyltransferase 5). It binds to a folded domain, amino acids 269-637. PRMT5 is a arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA.

Characteristics:

Original Species of Ab: Human

Original Format of Ab: Fab

Purification: Protein A affinity purified

Immunogen: This antibody was obtained by recombinant antibody (rAb) phage display recognizing PRMT5 protein under non-denaturing conditions.

Isotype: IgG kappa

Application Details

Application Notes: This antibody has been used and recommended for the following methods: ELISA, IF, IP-MS, ChIP.

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Human Fab format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for PRMT5

Target: PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

Alternative Name: PRMT5

Background: PRMT5, Protein arginine N-methyltransferase 5, 72 kDa ICln-binding protein, Histone-arginine N-methyltransferase PRMT5, Jak-binding protein 1, Shk1 kinase-binding protein 1 homolog, SKB1 homolog, SKB1Hs, anti-PRMT5-RAB-C136, 48F3_10

UniProt: O14744

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development