Recombinant CD37 antibody

Catalog No. ABIN7072735

This Rabbit Chimeric antibody specifically detects CD37 in Dep. It exhibits reactivity toward Human.

Quick Overview for Recombinant CD37 antibody (ABIN7072735)

Target: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This CD37 antibody is un-conjugated

Application: Depletion (Dep)

Clone: G28-1

Product Details anti-CD37 Antibody

Purpose: Anti-CD37 [G28-1], Rabbit IgG, kappa

Specificity: This antibody recognises CD37, which is a cell surface protein, present mostly on mature B cells and B cell malignancies.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogen: This antibody was raised by immunizing mice with CD37.

Isotype: IgG kappa

Application Details

Application Notes: G28-1 antibody was used to deplete normal and malignant B cells (Hayden-Ledbetter, unpublishesd). This antibody and antibody fragments derived therefrom have been used in the research and trials on the generation of novel immunotherapuetic agents, alternative to anti-CD20 therpaies (rituximab) (Robak and Robak, 2014).

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for CD37

Target: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Alternative Name: CD37

Background: TSPAN-26, Leukocyte antigen CD37, Tetraspanin-26, tetraspanin, Tspan-26

UniProt: P11049

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response