Recombinant Sialoadhesin/CD169 antibody
Quick Overview for Recombinant Sialoadhesin/CD169 antibody (ABIN7072742)
Target
See all Sialoadhesin/CD169 (SIGLEC1) AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Purpose
- Anti-CD169 [3D6.112 (recombinant version)], Rat IgG2a, kappa
-
Specificity
- This antibody specifically recognize mouse CD169, which is a 180-185- kDa member of the Siglec family of macrophage-specific cell adhesion and endocytic receptors interacting with sialylated glycans. This receptor is expressed on a subset of macrophages that are found with high frequency in the spleen, liver, lymph node, and bone marrow. CD169 can also be detected on monocytes in the bone marrow and periphery.
-
Characteristics
-
Original Species of Ab: Rat
Original Format of Ab: IgG2a
-
Purification
- Protein A affinity purified
-
Immunogen
- Spleen cells from AO rats immunised with thioglycollate-elicted murine peritoneal macrophages (TPM) that had been cutured in mouse serum to induce sheep erythrocyte receptor (SER).
-
Isotype
- IgG2a kappa
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Comment
-
This constant region of this antibody has been modified to bind to Protein A, allowing highly-specific purification of this antibody by Protein A-affinity column.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 1 mg/mL
-
Buffer
- PBS with 0.02 % Proclin 300.
-
Preservative
- ProClin
-
Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
-
-
- Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))
-
Alternative Name
- CD169
-
Background
- Sialoadhesin, Sheep erythrocyte receptor, SER, Sialic acid-binding Ig-like lectin 1, Siglec-1
-
UniProt
- Q62230
Target
-