ACTN1 antibody

Catalog No. ABIN7072905

The Rabbit Polyclonal anti-ACTN1 antibody is suitable to detect ACTN1 in samples from Human, Mouse and Rat. It has been validated for WB, IHC and IF.

Quick Overview for ACTN1 antibody (ABIN7072905)

Target: ACTN1 (Actinin, alpha 1 (ACTN1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACTN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ACTN1 Antibody

Cross-Reactivity: Mouse, Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Human alpha Actinin 1/ACTN1

Application Details

Application Notes: WB (H,M,R) 1:500-1:1000, IHC/IF (H,M,R) 1:300-1:600/1:300-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for ACTN1

Target: ACTN1 (Actinin, alpha 1 (ACTN1))

Alternative Name: alpha Actinin 1/ACTN1

Background: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane.This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene.

Molecular Weight: 103 kDa

Gene ID: 109711

NCBI Accession: NP_001093

UniProt: P12814

Pathways: Cell-Cell Junction Organization