BMP4 antibody

Catalog No. ABIN7073215

This anti-BMP4 antibody is a Rabbit Polyclonal antibody detecting BMP4 in IHC and IF. Suitable for Rat and Mouse.

Quick Overview for BMP4 antibody (ABIN7073215)

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-BMP4 Antibody

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse Mouse BMP4.

Application Details

Application Notes: IHC/IF (M,R) 1:1000-1:4000/1:1000-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for BMP4

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Alternative Name: BMP4

Background: BMP4 is a polypeptide belonging to the TGF-βsuperfamily of proteins, which binds to 2 different types of serine-threonine kinase receptors known as BMPR1 and BMPR2. Signal transduction via these receptors occurs via Smad and map kinase pathways to effect transcription of its target genes. Like other bone morphogenetic proteins, it is involved in bone and cartilage development, specifically tooth and limb development and fracture repair, playing an important role in the onset of endochondral bone formation in humans. It has been shown to be involved in muscle development, bone mineralization, and ureteric bud development.

Gene ID: 12159

NCBI Accession: NP_001303289

UniProt: P21275

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development