BSP antibody

Catalog No. ABIN7073219

This Rabbit Polyclonal antibody specifically detects BSP in IHC and IF. It exhibits reactivity toward Mouse and Rat.

Quick Overview for BSP antibody (ABIN7073219)

Target: BSP (Bone Sialoprotein (BSP))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BSP antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-BSP Antibody

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Bone Sialoprotein

Application Details

Application Notes: IHC/IF (M,R) 1:500-1:1500/1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for BSP

Target: BSP (Bone Sialoprotein (BSP))

Alternative Name: Bone Sialoprotein

Background: Bone sialoprotein (BSP) is a component of mineralized tissues such as bone, dentin, cementum and calcified cartilage. BSP is a significant component of the bone extracellular matrix and has been suggested to constitute approximately 8 % of all non-collagenous proteins found in bone and cementum. It is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.

Gene ID: 15891

NCBI Accession: NP_032344

UniProt: Q61711