PLAA antibody (AA 101-200) (HRP)

Catalog No. ABIN704420

The Rabbit Polyclonal anti-PLAA antibody has been validated for WB, ELISA, IHC (fro) and IHC (p). It is suitable to detect PLAA in samples from Human.

Quick Overview for PLAA antibody (AA 101-200) (HRP) (ABIN704420)

Target: PLAA (Phospholipase A2-Activating Protein (PLAA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLAA antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PLAA Antibody (HRP)

Binding Specificity: AA 101-200

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Phospholipase A2 activator protein

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PLAA

Target: PLAA (Phospholipase A2-Activating Protein (PLAA))

Alternative Name: PLAA/Phospholipase A2 activator protein

Background:

Synonyms: DOA1, PLAP, PLA2P, Phospholipase A-2-activating protein, PLAA

Background: Phospholipase A2 activator protein (PLAP), activates PLA2 (phospholipase A2 enzyme) and is an important mediator of eicosanoid generation. Also known as a pro-inflammatory agent, PLAP has been found in inflamed tissues and synovial fluid from patients with rheumatoid arthritis. As such, it is believed to play an important role in the regulation of inflammatory diseases. The formation of PLAP can be stimulated by IL-1 beta and TNF-alpha.

Gene ID: 9373

UniProt: Q9Y263