Calcineurin A antibody

Catalog No. ABIN7073270

This Rabbit Polyclonal antibody specifically detects Calcineurin A in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Calcineurin A antibody (ABIN7073270)

Target: Calcineurin A (CAN)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calcineurin A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Calcineurin A Antibody

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Calcineurin A

Application Details

Application Notes: WB (H,M,R) 1: 1000-1: 2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for Calcineurin A

Target: Calcineurin A (CAN)

Alternative Name: Calcineurin A

Background: Calcineurin, a major soluble calmodulin binding protein in the brain, a Ca2+/calmodulin dependent serine/threonine protein phosphatase, with a relatively narrow substrate specificity. This metalloenzyme, also known as phosphatase 2B, is a heterodimer composed of a calmodulin binding, catalytic alpha subunit 61 kDa, calcineurin A) and calcium binding beta subunit (18 kDa, calcineurin B). The Ca2+ binding subunit, calcineurin B, is immunologically conserved from yeast to mammals. The presence of 2 different calcineurin B isoforms (beta 1 and beta 2) has been reported in rat testis. The catalytic subunit of calcineurin, calcineurin A, isolated from different tissues or different organisms, exhibits some immunological heterogeneity.

Molecular Weight: 59 kDa

Gene ID: 19055

NCBI Accession: NP_001280551

UniProt: P63328