CD5L antibody

Catalog No. ABIN7073398

This anti-CD5L antibody is a Rabbit Polyclonal antibody detecting CD5L in WB. Suitable for Rat.

Quick Overview for CD5L antibody (ABIN7073398)

Target: CD5L (CD5 Molecule-Like (CD5L))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD5L antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD5L Antibody

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse CD5L/CT-2

Application Details

Application Notes: WB (R) 1:700-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for CD5L

Target: CD5L (CD5 Molecule-Like (CD5L))

Alternative Name: CD5L/CT-2

Background: CD5L is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that CD5L functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. CD5L was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombinant CD5L significantly inhibited apoptosis of NKT and T cells obtained from C. parvum-stimulated livers in vitro, suggesting that CD5L functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection. Expressed in spleen, lymph node, thymus, bone marrow, and fetal liver, but not in non-lymphoid tissues.

Molecular Weight: 46 kDa

Gene ID: 11801

NCBI Accession: NP_033820

UniProt: Q9QWK4