DEPDC1
Reactivity: Mouse
WB, IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 594
Application Notes
IHC/IF (M,R) 1:500-1:1500/1:500-1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, pH 7.4, 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Target
DEPDC1
(DEP Domain Containing 1 (DEPDC1))
Alternative Name
DEPDC1
Background
DEPDC1 is a 784 amino acid nuclear protein expressed in testis and up-regulated in bladder cancer cells. Containing a DEP domain and a Rho-GAP domain, DEPDC1 may play an essential role in the growth of bladder cancer cells, and is considered a novel protein target for bladder cancer therapy. Existing as five isoforms produced by alternative splicing events, DEPDC1 is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome.