EMAP-II/AIMP1 antibody
Quick Overview for EMAP-II/AIMP1 antibody (ABIN7073814)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human
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Purification
- Affinity purification
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Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse EMAP II/AIMP1
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Application Notes
- WB (H) 1,1000-1,2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- EMAP-II/AIMP1
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Alternative Name
- EMAP II/AIMP1
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Background
- SCYE1(small inducible cytokine subfamily E, member 1) is also named as EMAP2, AIMP1. The human cDNA encodes a 312-amino acid polypeptide that the predicted 34- kDa precursor can be cleaved to produce an active 20- kDa product. SCYE1 is secreted as a result of various stimuli, including TNF-α, heat shock, and hypoxia, and that it acts as a multifunctional cytokine on both endothelial and immune cells. Defects in AIMP1 are the cause of leukodystrophy hypomyelinating type 3 (HLD3). It has 2 isoforms produced by alternative splicing and the protein can exsit as a dimer.
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Molecular Weight
- 40 kDa
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UniProt
- P31230
Target
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