ETF1 antibody
Quick Overview for ETF1 antibody (ABIN7073895)
Target
See all ETF1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human, Rat
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Purification
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse eRF1
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Application Notes
- WB (H,M,R) 1 :500-1: 1000, IHC/IF (R) 1:1500-1:4000/1:750-1:1500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- ETF1 (Eukaryotic Translation Termination Factor 1 (ETF1))
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Alternative Name
- eRF1
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Background
- This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in coding and non-coding transcript variants. Pseudogenes of this gene are found on chromosomes 5, 7 and X.
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Molecular Weight
- 50 kDa
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Gene ID
- 225363
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NCBI Accession
- NP_659115
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UniProt
- Q8BWY3
Target
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