FCRL5
Reactivity: Human
Host: Rabbit
Polyclonal
FITC
Application Notes
IHC/IF (H) 1:200-1:1000/1:200-1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, pH 7.4, 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Target
FCRL5
(Fc Receptor-Like 5 (FCRL5))
Alternative Name
FCRL5
Background
FCRL5, also known as CD307 or IRTA2, is a surface protein expressed selectively on B cells and plasma cells . This protein has both an immunoreceptor tyrosine-based activation motif (ITAM)-like sequence and two consensus immunoreceptor tyrosine-based inhibitory motifs (ITIM) in its cytoplasmic region . FCRL5 is implicated in B cell development and lymphomagenesis . It may have an immunoregulatory role in marginal zone B-cells.