FOXL2 antibody

Catalog No. ABIN7073971

This anti-FOXL2 antibody is a Rabbit Polyclonal antibody detecting FOXL2 in IHC and IF. Suitable for Mouse.

Quick Overview for FOXL2 antibody (ABIN7073971)

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXL2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-FOXL2 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse FOXL2

Application Details

Application Notes: IHC/IF (M) 1:3000-1:6000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for FOXL2

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Alternative Name: FOXL2

Background: Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis throught transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR.

Gene ID: 26927

UniProt: O88470

Pathways: Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity