KIF5B antibody

Catalog No. ABIN7074440

This Rabbit Polyclonal antibody specifically detects KIF5B in WB, IHC and IF. It exhibits reactivity toward Mouse and Rat.

Quick Overview for KIF5B antibody (ABIN7074440)

Target: KIF5B (Kinesin Family Member 5B (KIF5B))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIF5B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-KIF5B Antibody

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse KIF5B

Application Details

Application Notes: WB (M,R) 1:2000-1:4000, IHC/IF (M,R) 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for KIF5B

Target: KIF5B (Kinesin Family Member 5B (KIF5B))

Alternative Name: KIF5B

Background: Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. May be involved in the mechanisms of growth arrest induced by exposure to DNA-damaging drugs or by cellular senescence . Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner . Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation .

Molecular Weight: 130 kDa

Gene ID: 16573

NCBI Accession: NP_032474

UniProt: Q61768

Pathways: Peptide Hormone Metabolism, Ribonucleoprotein Complex Subunit Organization