Mitochondrial Inner Membrane Protease ATP23 Homolog (ATP23) antibody
Quick Overview for Mitochondrial Inner Membrane Protease ATP23 Homolog (ATP23) antibody (ABIN7074637)
Target
Reactivity
Host
Clonality
Application
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Cross-Reactivity
- Rat
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Purification
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse XRCC6BP1/KUB3
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Application Notes
- WB (M,R) 1: 1000-1: 2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- Mitochondrial Inner Membrane Protease ATP23 Homolog (ATP23)
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Alternative Name
- XRCC6BP1/KUB3
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Background
- The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 30 kDa
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Gene ID
- 68876
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NCBI Accession
- NP_081134
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UniProt
- Q9CWQ3
Target
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