NAD-ME antibody

Catalog No. ABIN7074757

This anti-NAD-ME antibody is a Rabbit Polyclonal antibody detecting NAD-ME in IHC and IF. Suitable for Human and Rat.

Quick Overview for NAD-ME antibody (ABIN7074757)

Target: NAD-ME (NAD Dependent Malate Dehydrogenase (NAD-ME))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAD-ME antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-NAD-ME Antibody

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse ME2

Application Details

Application Notes: IHC/IF (H,R) 1:3000-1:6000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for NAD-ME

Target: NAD-ME (NAD Dependent Malate Dehydrogenase (NAD-ME))

Alternative Name: ME2

Background: ME2(malic enzyme 2) is also named as NAD-ME and belongs to the malic enzymes family. ME1, ME2 are important for NADPH production, lipogenesis and glutamine metabolism, but ME2 has a more profound effect. ME2 is a genome-coded mitochondrial enzyme that converts malate to pyruvate and is involved in neuronal synthesis of the neurotransmitter γ-aminobutyric acid (GABA). This protein has 2 isoforms produced by alternative splicing with the MW of 65 kDa and 54 kDa.

Gene ID: 107029

NCBI Accession: NP_663469

UniProt: Q99KE1

Pathways: Production of Molecular Mediator of Immune Response