PTGDR antibody

Catalog No. ABIN7075206

The Rabbit Polyclonal anti-PTGDR antibody is suitable to detect PTGDR in samples from Mouse and Rat. It has been validated for WB.

Quick Overview for PTGDR antibody (ABIN7075206)

Target: PTGDR (Prostaglandin D2 Receptor (PTGDR))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGDR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PTGDR Antibody

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Prostaglandin D2 Receptor

Application Details

Application Notes: WB (M,R) 1:1000-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for PTGDR

Target: PTGDR (Prostaglandin D2 Receptor (PTGDR))

Alternative Name: Prostaglandin D2 Receptor

Background: Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate . Involved in PLA2G3-dependent maturation of mast cells. PLA2G3 is secreted by immature mast cells and acts on nearby fibroblasts upstream to PTDGS to synthesize PGD2, which in turn promotes mast cell maturation and degranulation via PTGDR.

Molecular Weight: 50 kDa

Gene ID: 19214

NCBI Accession: NP_032988

UniProt: P70263

Pathways: Thromboxane A2 Receptor Signaling