STRADA antibody

Catalog No. ABIN7075730

This Rabbit Polyclonal antibody specifically detects STRADA in WB, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for STRADA antibody (ABIN7075730)

Target: STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STRADA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-STRADA Antibody

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse STRAD

Application Details

Application Notes: WB (H,M,R) 1:500-1:1000, IHC/IF (M,R) 1:600-1:1200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for STRADA

Target: STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

Alternative Name: STRAD

Background: LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating the tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. LYK5-LKB1 interaction results in phosphorylation of LYK5 and enhanced autophosphorylation of LKB1.

Molecular Weight: 48 kDa

Gene ID: 72149

NCBI Accession: NP_001239377

UniProt: Q3UUJ4

Pathways: AMPK Signaling