tau antibody (pSer202, pThr205)
Quick Overview for tau antibody (pSer202, pThr205) (ABIN7075838)
Target
See all tau AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer202, pThr205
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Cross-Reactivity
- Mouse, Rat
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Purification
- Affinity purification
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Immunogen
- KLH conjugated Synthetic phosphopeptide corresponding to Human TAU (S202/T205)
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Application Notes
- WB (H,M,R) 1:500-1:1000, IHC/IF (H,M,R) 1:600-1:1200
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Restrictions
- For Research Use only
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Buffer
- , 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- tau (tau Protein)
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Alternative Name
- TAU
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Background
- Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity .The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both .Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
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Molecular Weight
- 50-80 kDa
Target
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