Histone H4 antibody (AA 51-103)

Catalog No. ABIN704681

There is 1 publication for this product available. The Rabbit Polyclonal anti-Histone H4 antibody is suitable to detect Histone H4 in samples from Human and Rat. It has been validated for ELISA and FACS.

Quick Overview for Histone H4 antibody (AA 51-103) (ABIN704681)

Target: Histone H4 (HISTH4)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H4 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Product Details anti-Histone H4 Antibody

Binding Specificity: AA 51-103

Predicted Reactivity: Mouse,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Histone H4

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Histone H4 antibody (ABIN704681)

Qian, Zhang, Hu, Xu, Chen, Hu, Zhao, Liu: "Silver nanoparticle-induced hemoglobin decrease involves alteration of histone 3 methylation status." in: Biomaterials, Vol. 70, pp. 12-22, (2015) (PubMed).

Target Details for Histone H4

Target: Histone H4 (HISTH4)

Alternative Name: Histone H4

Background:

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Subcellular location: Nucleus

Synonyms: H4/p, Histone H4, HIST1H4A, H4/A, H4FA

Gene ID: 121504

UniProt: P62805