TRIM26 antibody

Catalog No. ABIN7076014

Cited in 1 publication. This anti-TRIM26 antibody is a Rabbit Polyclonal antibody detecting TRIM26 in WB. Suitable for Human, Mouse and Rat.

Quick Overview for TRIM26 antibody (ABIN7076014)

Target: TRIM26 (Tripartite Motif Containing 26 (TRIM26))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM26 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRIM26 Antibody

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse TRIM26

Application Details

Application Notes: WB (H,M,R) 1:1000-1:1500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-TRIM26 antibody (ABIN7076014)

Xu, Tan, Liu, Han, Ge, Zhang, Luo, Wang, Xue, Xiong, Wang, Zhang, Wang, Tian, Zhang, Meng, Dai, Kuang, Li, Lou, Hu, Liu, Kuang, Luo, Chang, Wang, Chai, Shi, Han: "Tripartite motif containing 26 prevents steatohepatitis progression by suppressing C/EBPδ signalling activation." in: Nature communications, Vol. 14, Issue 1, pp. 6384, (2023) (PubMed).

Target Details for TRIM26

Target: TRIM26 (Tripartite Motif Containing 26 (TRIM26))

Alternative Name: TRIM26

Background: TRIM26 is a member of the tripartite motif (TRIM) protein family composed of more than 70 members in human. TRIM proteins share a similar characteristic structure, which includes a RING (R) domain, one or two B-boxes (B), and a coiled coil (CC) domain in the N-terminal and a domain in the C-terminal with variable structures. TRIM26 potentiates virus-triggered IRF3, NF-κB activation, IFN-β induction, and cellular antiviral responses. Further investigation suggests that TRIM26 plays an important role in the antiviral innate immune response by bridging TBK1 to NEMO and mediating TBK1 activation.

Molecular Weight: 63 kDa

Gene ID: 22670

NCBI Accession: NP_001020770

UniProt: Q99PN3