ube3a antibody
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- Target See all ube3a Antibodies
- ube3a (Ubiquitin Protein Ligase E3A (ube3a))
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ube3a antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Rat
- Purification
- Affinity purification
- Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse UBE3A
- Top Product
- Discover our top product ube3a Primary Antibody
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anti-Ubiquitin Protein Ligase E3A (ube3a) (AA 51-150) antibody
ube3a Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 2F6 unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) antibodyube3a Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) (AA 836-865), (C-Term) antibodyube3a Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB4440 unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) antibodyube3a Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) (AA 300-590) antibodyube3a Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) (Middle Region) antibodyube3a Reactivity: Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Cow WB Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) (AA 83-234) antibodyube3a Reactivity: Human IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) antibodyube3a Reactivity: Human IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) antibodyube3a Reactivity: Human WB, IHC, IF/ICC, FACS Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) (AA 158-407) antibodyube3a Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- IHC/IF (M,R) 1:1000-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- ube3a (Ubiquitin Protein Ligase E3A (ube3a))
- Alternative Name
- UBE3A (ube3a Products)
- Background
- UBE3A (ubiquitin-protein ligase E3A, AKA E6AP) is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the ARNTL/BMAL1, ARC, RAD23A, RAD23B, MCM7, annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B. Additionally, UBE3A may function as a cellular quality control ubiquitin ligase by helping the degradation of the cytoplasmic misfolded proteins. UBE3A also plays an important role in the regulation of the circadian clock. Defects in UBE3A are a cause of Angelman syndrome (AS).
- Gene ID
- 22215
- NCBI Accession
- NP_035798
- UniProt
- O08759
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
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