Vegf Receptor 3 antibody
Quick Overview for Vegf Receptor 3 antibody (ABIN7076194)
Target
Reactivity
Host
Clonality
Application
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Cross-Reactivity
- Human, Rat
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Purification
- Affinity purification
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Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse VEGF Receptor 3
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Application Notes
- WB (H) 1:500-1:1000, IHC/IF (M,R) 1:400-1:1200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- Vegf Receptor 3
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Background
- Vascular endothelial growth factors (VEGFs) are a family of closely related growth factors having a conserved pattern of eight cysteine esidues and sharing common VEGF receptors. VEGFs stimulate the proliferation of endothelial cells, induce angiogenesis, and increase vascular permeability in both large and small vessels. The mitogenic activity of VEGFs appears to be mediated by specific VEGF receptors. VEGF Receptor 3 is one of the five receptor tyrosine kinases (RTKs) (VEGF Receptor 1/Flt1, VEGF Receptor 2/KDR/Flk1, VEGF Receptor 3/Flt4, tie1 and tek/tie2) whose expression is almost exclusively restricted to endothelial cells.
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Molecular Weight
- 130 kDa
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Gene ID
- 14257
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NCBI Accession
- NP_032055
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UniProt
- P35917
Target
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