WDR59 antibody

Catalog No. ABIN7076219

This Rabbit Polyclonal antibody specifically detects WDR59 in WB. It exhibits reactivity toward Mouse and Rat.

Quick Overview for WDR59 antibody (ABIN7076219)

Target: WDR59 (WD Repeat Domain 59 (WDR59))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR59 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-WDR59 Antibody

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse WDR59

Application Details

Application Notes: WB (M,R) 1: 500-1: 1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for WDR59

Target: WDR59 (WD Repeat Domain 59 (WDR59))

Alternative Name: WDR59

Background: As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1.

Molecular Weight: 112 kDa

Gene ID: 319481

NCBI Accession: NP_001164213

UniProt: Q8C0M0