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CD59 antibody (FITC)

The Mouse Monoclonal anti-CD59 antibody has been validated for FACS. It is suitable to detect CD59 in samples from Human.
Catalog No. ABIN7076677

Quick Overview for CD59 antibody (FITC) (ABIN7076677)

Target

See all CD59 Antibodies
CD59

Reactivity

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Human

Host

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Mouse

Clonality

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Monoclonal

Conjugate

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This CD59 antibody is conjugated to FITC

Application

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Flow Cytometry (FACS)

Grade

GMP Grade (Analyte)

Clone

BRA-10G
  • Purpose

    CD59 FITC Antibody

    Characteristics

    The clone BRA-10G binds with human CD59, a 20 kDa glycosyl phosphatidyl-inositol (GPI)-anchored cell surface protein. CD59 regulates complement-mediated cell lysis and is a potent inhibitor of the complement membrane attack complex. CD59 is widely distributed on cells in all tissues. The CD59 expression on erythrocytes is important for their survival. Genetic defects in GPI-anchor attachment, that cause a reduction or loss of CD59 and CD55 on erythrocytes produce the symptoms of the disease paroxysmal hemoglobinuria (PNH). This MAb is useful for study on GPI-anchored proteins, PNH and CD59 functions.

    Purification

    Purified

    Purity

    >95 %

    Immunogen

    Human K562 tumor cells

    Isotype

    IgG1, kappa
  • Application Notes

    FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Storage Comment

    2-8°C, Conjugated antibodies should never be frozen.
  • Target

    CD59

    Alternative Name

    CD59

    Gene ID

    966

    NCBI Accession

    NP_000602, NP_001120695, NP_001120697, NP_001120698, NP_001120699, NP_976074, NP_976075, NP_976076

    UniProt

    P13987

    Pathways

    Complement System
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