CD59 antibody (FITC)
Quick Overview for CD59 antibody (FITC) (ABIN7076677)
Target
See all CD59 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
Clone
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Purpose
- CD59 FITC Antibody
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Characteristics
- The clone BRA-10G binds with human CD59, a 20 kDa glycosyl phosphatidyl-inositol (GPI)-anchored cell surface protein. CD59 regulates complement-mediated cell lysis and is a potent inhibitor of the complement membrane attack complex. CD59 is widely distributed on cells in all tissues. The CD59 expression on erythrocytes is important for their survival. Genetic defects in GPI-anchor attachment, that cause a reduction or loss of CD59 and CD55 on erythrocytes produce the symptoms of the disease paroxysmal hemoglobinuria (PNH). This MAb is useful for study on GPI-anchored proteins, PNH and CD59 functions.
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Purification
- Purified
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Purity
- >95 %
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Immunogen
- Human K562 tumor cells
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Isotype
- IgG1, kappa
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Application Notes
- FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- 2-8°C, Conjugated antibodies should never be frozen.
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- CD59
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Alternative Name
- CD59
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Gene ID
- 966
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NCBI Accession
- NP_000602, NP_001120695, NP_001120697, NP_001120698, NP_001120699, NP_976074, NP_976075, NP_976076
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UniProt
- P13987
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Pathways
- Complement System
Target
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