CD34 antibody (FITC)

Catalog No. ABIN7077139

Product Details anti-CD34 Antibody (FITC)

Target: CD34

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD34 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Purpose: CD34 FITC Antibody

Characteristics: The clone 4H11, a mouse monoclonal antibody recognizes a human ~115 KDa monomeric transmembrane phosphoglycoprotein commonly known as CD34. It is expressed mostly on hematopoietic progenitors and pluripotent stem cells, and in multitude of other nonhematopoietic cell types including muscle satellite cells, corneal keratocytes, interstitial cells, epithelial progenitors, and vascular endothelial progenitors. The anti-CD34 binding affinity has been assigned to three classes (class I, II or III) based on their neuraminidase and glycoprotease sensitivity response and 4H11 is considered as class III antibody. In clinical practice, CD34 expression is evaluated to ensure rapid engraftment in BM transplants and can also be used as a selective marker in cell sorting to enrich a population of immature hematopoietic cells.

Purification: Purified

Purity: >95 %

Grade: GMP Grade

Immunogen: Human cell line derived from peripheral leukocytes from a CML patient

Clone: 4H11

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C, Conjugated antibodies should never be frozen.

Target Details for CD34

Target: CD34

Alternative Name: CD34 (CD34 Products)

Gene ID: 947

UniProt: P28906