CD45RO antibody (mFluor™450)
Quick Overview for CD45RO antibody (mFluor™450) (ABIN7077263)
Target
Reactivity
Host
Clonality
Conjugate
Application
Grade
Clone
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Purpose
- CD45RO mFluor450 Antibody
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Characteristics
- The clone UCHL1 recognizes 180-185 KD surface antigen known as CD45RO commonly expressed by thymocytes, a subset of resting, memory and activated T cells, activated monocytes/macrophages, granulocytes and myeloma cells. CD45RO is the shortest isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. It plays important rule in development of lymphocytes and antigen signaling, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis.
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Purification
- Purified
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Purity
- >95 %
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Immunogen
- IL-2 dependent T cell line, CA-1
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Isotype
- IgG2a, kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- 2-8°C, Conjugated antibodies should never be frozen.
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- CD45RO
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Alternative Name
- CD45RO
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Gene ID
- 5788
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UniProt
- P08575
Target
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