KCNJ6 antibody

Catalog No. ABIN705341

The Rabbit Polyclonal anti-KCNJ6 antibody has been validated for WB. It is suitable to detect KCNJ6 in samples from Human, Mouse and Rat.

Quick Overview for KCNJ6 antibody (ABIN705341)

Target: KCNJ6 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 (KCNJ6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNJ6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KCNJ6 Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GIRK2

Isotype: IgG

Application Details

Application Notes: WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for KCNJ6

Target: KCNJ6 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 (KCNJ6))

Alternative Name: Girk2

Background:

Synonyms: inwardly rectying subfamily J member 6, Kir3.2, BIR1, G protein activated inward rectier potassium channel 2, G protein-activated inward rectier potassium channel 2, GIRK-2, Inward rectier K+ channel Kir3.2, IRK6_HUMAN, KATP-2, Kcnj6, Kcnj7, Potassium channel, Potassium channel inwardly rectying subfamily J member 6.

Background: This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

Gene ID: 3763