DDIT4 antibody (AA 165-232) (HRP)

Catalog No. ABIN705740

The Rabbit Polyclonal anti-DDIT4 antibody has been validated for ELISA, IHC (p) and IHC (fro). It is suitable to detect DDIT4 in samples from Rat.

Quick Overview for DDIT4 antibody (AA 165-232) (HRP) (ABIN705740)

Target: DDIT4 (DNA-Damage-Inducible Transcript 4 (DDIT4))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDIT4 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-DDIT4 Antibody (HRP)

Binding Specificity: AA 165-232

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DDIT4

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DDIT4

Target: DDIT4 (DNA-Damage-Inducible Transcript 4 (DDIT4))

Alternative Name: DDIT4

Background:

Synonyms: DDIT4, DDIT4_HUMAN, Dig2, DKFZp564O2071, DNA damage inducible transcript 4, DNA damage inducible transcript 4 protein, DNA damage-inducible transcript 4 protein, FLJ20500, H 1 responsive protein RTP801, H 1 responsive RTP801, H-1 responsive protein RTP801, Protein regulated in development and DNA damage response 1, REDD 1, REDD-1, REDD1, RP11 442H21.1, RTP801.

Background: Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. Promotes neuronal cell death.

Gene ID: 54541

Pathways: Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process