TRIP10 antibody (AA 151-250)

Catalog No. ABIN706121

The Rabbit Polyclonal anti-TRIP10 antibody has been validated for WB, ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). It is suitable to detect TRIP10 in samples from Mouse.

Quick Overview for TRIP10 antibody (AA 151-250) (ABIN706121)

Target: TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIP10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-TRIP10 Antibody

Binding Specificity: AA 151-250

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Cip4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TRIP10

Target: TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))

Alternative Name: Cip4

Background:

Synonyms: Cdc42 interacting protein 4, Cdc42 interaction protein 4 long isoform, Cdc42-interacting protein 4, Cip 4, CIP4_HUMAN, DCIP4, hSTP, Protein Felic, Salt tolerant protein, Salt tolerator, STOT, STP, Thyroid hormone receptor interactor 10, Thyroid receptor interacting protein 10, Thyroid receptor-interacting protein 10, TR-interacting protein 10, TRIP 10, TRIP-10, trip10, Truncated Cdc42 interaction protein 4.

Background: Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.

Gene ID: 9322