CEACAM1 antibody

Catalog No. ABIN7090813

The Rabbit Monoclonal anti-CEACAM1 antibody has been validated for IHC (p). It is suitable to detect CEACAM1 in samples from Human.

Quick Overview for CEACAM1 antibody (ABIN7090813)

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CEACAM1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: A10D5

Product Details anti-CEACAM1 Antibody

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD66a

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CEACAM1

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Alternative Name: CD66a

Background:

Synonyms: CEACAM1, carcinoembryonic antigen-related cell adhesion molecule 1 isoform 1 precursor, Antigen CD66, BGP, BGP 1, BGP I, BGP1,BGPI, Biliary glycoprotein 1, Biliary glycoprotein adhesion molecule, Biliary glycoprotein, Carcinoembryonic antigen related cell adhesion molecule 1, CD66 antigen, CD66a antigen, CEACAM 1, bb-1, C-CAM, Cc1, Cea-1, Cea-7, Cea1, Cea7, Hv-2, Hv2, mCEA1, Mhv-1, MHVR, MHVR1, mmCGM1, mmCGM1a, mmCGM2, CEAM1_HUMAN.

Background: This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined. [provided by RefSeq, May 2010].

Gene ID: 634

UniProt: P13688