CD2 antibody

Catalog No. ABIN7090867

The Rabbit Monoclonal anti-CD2 antibody has been validated for IF and ICC. It is suitable to detect CD2 in samples from Human.

Quick Overview for CD2 antibody (ABIN7090867)

Target: CD2

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD2 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: C11G5

Product Details anti-CD2 Antibody

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD2

Isotype: IgG

Application Details

Application Notes: IF()
ICC 1:100-500

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CD2

Target: CD2

Alternative Name: CD2

Background:

Synonyms: T-cell surface antigen CD2, CD 2, CD2 antigen, CD2 Molecule, LFA2, LFA3 receptor, Lymphocyte function antigen 2, p50, Rosette receptor, Sheep erythrocyte receptor, Sheep red blood cell receptor, SRBC, T cell surface antigen CD2, T cell surface antigen T11/Leu 5, T11, CD2_HUMAN.

Background: CD2 is a surface antigen of the human T lymphocyte lineage that is expressed on all peripheral blood T cells. It is one of the earliest T cell markers, being present on more than 95 % of thymocytes, it is also found on some natural killer cells but not on B lymphocytes.
CD2 interacts with lymphocyte function associated antigen (LFA3) and CD48/BCM1 to mediate adhesion between T cells and other cell types. CD2 is implicated in the triggering of T cells, the cytoplasmic domain is implicated in the signaling function. It is useful for the identification of lymphomas and leukaemias of T cell origin.

Gene ID: 914

UniProt: P06729