CD3 antibody (AbBy Fluor® 750)

Catalog No. ABIN7090898

This anti-CD3 antibody is a Mouse Monoclonal antibody detecting CD3 in FACS. Suitable for Human.

Quick Overview for CD3 antibody (AbBy Fluor® 750) (ABIN7090898)

Target: CD3

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD3 antibody is conjugated to AbBy Fluor® 750

Application: Flow Cytometry (FACS)

Clone: HIT3b

Product Details anti-CD3 Antibody (AbBy Fluor® 750)

Cross-Reactivity: Human

Purification: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human CD3

Isotype: IgG1

Application Details

Application Notes: FCM 1:20-100

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Target Details for CD3

Target: CD3

Alternative Name: CD3

Background:

Synonyms: CD3e Molecule, CD3e Antigen, Epsilon Polypeptide (TiT3 Complex), T-Cell Surface Antigen T3/Leu-4 Epsilon Chain, CD3e Molecule, Epsilon (CD3-TCR Complex), T3E, T-Cell Antigen Receptor Complex, Epsilon Subunit Of T3, T-Cell Surface Glycoprotein CD3 Epsilon Chain, CD3e Antigen, CD3-Epsilon, IMD18, TCRE,

Background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].

Gene ID: 12501

UniProt: P22646

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway