CCR4 antibody (AA 171-220) (Biotin)

Catalog No. ABIN7090976

This anti-CCR4 antibody is a Rabbit Polyclonal antibody detecting CCR4 in ELISA, WB, IHC (p) and IHC (fro). Suitable for Human and Rat.

Quick Overview for CCR4 antibody (AA 171-220) (Biotin) (ABIN7090976)

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR4 antibody is conjugated to Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CCR4 Antibody (Biotin)

Binding Specificity: AA 171-220

Cross-Reactivity: Human, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCR4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CCR4

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Alternative Name: CCR4

Background:

Synonyms: CC chemokine receptor 4, chemokine (C-C motif) receptor 4, CC-CKR-4, CCR-4, CD194, CHEMOKINE CC4 RECEPTOR, CHEMR1, ChemR13, CKR4, CMKBR4, HGCN:14099, K5-5, LESTR, MGC151418, MGC88293, nocturnin, Sdf1r, chemokine C C motif receptor 4, ChemR13, CCR4_HUMAN, C-C chemokine receptor type 4, K5-5, CD 194, CD-194.

Background: High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.

Gene ID: 1233

UniProt: P51679