CCR4 antibody (AA 171-220)

Catalog No. ABIN7090977

This Rabbit Polyclonal antibody specifically detects CCR4 in ELISA, WB, IHC (p), IF, IHC (fro) and ICC. It exhibits reactivity toward Human and Rat.

Quick Overview for CCR4 antibody (AA 171-220) (ABIN7090977)

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-CCR4 Antibody

Binding Specificity: AA 171-220

Cross-Reactivity: Human, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCR4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF()
ICC 1:100-500

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CCR4

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Alternative Name: CCR4

Background:

Synonyms: CC chemokine receptor 4, chemokine (C-C motif) receptor 4, CC-CKR-4, CCR-4, CD194, CHEMOKINE CC4 RECEPTOR, CHEMR1, ChemR13, CKR4, CMKBR4, HGCN:14099, K5-5, LESTR, MGC151418, MGC88293, nocturnin, Sdf1r, chemokine C C motif receptor 4, ChemR13, CCR4_HUMAN, C-C chemokine receptor type 4, K5-5, CD 194, CD-194.

Background: High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.

Gene ID: 1233

UniProt: P51679