CYP11B2 antibody (AA 221-320)

Catalog No. ABIN7091020

The Rabbit Polyclonal anti-CYP11B2 antibody has been validated for WB, ELISA, IHC (p), IF, IHC (fro) and ICC. It is suitable to detect CYP11B2 in samples from Human.

Quick Overview for CYP11B2 antibody (AA 221-320) (ABIN7091020)

Target: CYP11B2 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP11B2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-CYP11B2 Antibody

Binding Specificity: AA 221-320

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CYP11B2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF()
ICC 1:100-500

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CYP11B2

Target: CYP11B2 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))

Alternative Name: CYP11B2

Background:

Synonyms: CYP 11B2, CYP11B2, CYPXI11B2, Cytochrome P450 1111B2, Cytochrome P450 1111B2 mitochondrial, Cytochrome P450 family 11 subfamily B polypeptide 2, Cytochrome P450 subfamily XIB (cholesterol side chain cleavage), Cytochrome P450 subfamily XI11B2, Cytochrome P450C1111B2, C11B2_HUMAN.

Background: Preferentially catalyzes the conversion of 11-deoxycorticosterone to aldosterone via corticosterone and 18-hydroxycorticosterone.

Gene ID: 1585

UniProt: P19099

Pathways: ACE Inhibitor Pathway, Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process, Feeding Behaviour