Fission 1 antibody

Catalog No. ABIN7091113

The Mouse Monoclonal anti-Fission 1 antibody has been validated for WB, IF, ICC and IHC (p). It is suitable to detect Fission 1 in samples from Human.

Quick Overview for Fission 1 antibody (ABIN7091113)

Target: Fission 1 (FIS1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fission 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: B5E12

Product Details anti-Fission 1 Antibody

Cross-Reactivity: Human

Predicted Reactivity: Mouse

Purification: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human FIS1

Isotype: IgG1, kappa

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF()
ICC 1:100-500

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Fission 1

Target: Fission 1 (FIS1)

Alternative Name: FIS1

Background:

Synonyms: CGI 135, CGI135, FIS 1, FIS1, Fis1 homolog, FIS1, S. cerevisiae, homolog of, FIS1_HUMAN, Fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae), Fission 1 (mitochondrial outer membrane) homolog (yeast), Fission 1 (mitochondrial outer membrane) homolog, Fission 1 homolog, hFis 1 hFis1, Mitochondrial fission 1 protein, Tetratricopeptide repeat domain 11, Tetratricopeptide repeat protein 11, TPR repeat protein 11, TTC 11.

Background: The balance between fission and fusion regulates the morphology of mitochondria. TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission (James et al., 2003 [PubMed 12783892]).[supplied by OMIM, Mar 2008]

Gene ID: 51024

UniProt: Q9Y3D6

Pathways: Positive Regulation of Endopeptidase Activity