Galectin 3 antibody (AA 1-250) (Biotin)

Catalog No. ABIN7091152

The Rabbit Polyclonal anti-Galectin 3 antibody has been validated for WB. It is suitable to detect Galectin 3 in samples from Human.

Quick Overview for Galectin 3 antibody (AA 1-250) (Biotin) (ABIN7091152)

Target: Galectin 3 (LGALS3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Galectin 3 antibody is conjugated to Biotin

Application: Western Blotting (WB)

Product Details anti-Galectin 3 Antibody (Biotin)

Binding Specificity: AA 1-250

Cross-Reactivity: Human

Purification: affinity Purified by Protein A.

Immunogen: Recombinant human Galectin-3 protein

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Galectin 3

Target: Galectin 3 (LGALS3)

Alternative Name: Galectin 3

Target Type: Chemical

Background:

Synonyms: Galectin-3, 35 kDa lectin, Carbohydrate binding protein 35, CBP 35, CBP35, GAL 3, GAL3, GAL-3, Galactose specific lectin 3, Galactose-specific lectin 3, Galactoside binding protein, Galactoside-binding protein, GALBP, Galectin3 internal gene,included, Galectin3, GALIG, GBP, IgE binding protein, IgE-binding protein, L 31, L 34, L-34 galactoside-binding lectin, L31, Laminin binding protein, Laminin-binding protein, Lectin galactose binding soluble 3, Lectin galactoside binding soluble 3, Lectin L 29, Lectin L-29, Lectin, galactose binding, soluble 3, LGALS 3, LGALS2, LGALS3, LGALS3 protein, MAC 2 antigen, Mac-2, MAC2, Macrophage galactose-specific lectin, MGC105387, LEG3_HUMAN.

Background: Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.

Gene ID: 3958

UniProt: P17931

Pathways: RTK Signaling