GDF11 antibody

Catalog No. ABIN7091177

The Mouse Monoclonal anti-GDF11 antibody (Clone C4F5) (ABIN7091177) specifically detects GDF11 in WB. The antibody is reactive with Human samples.

Quick Overview for GDF11 antibody (ABIN7091177)

Target: GDF11 (Growth Differentiation Factor 11 (GDF11))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GDF11 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: C4F5

Product Details anti-GDF11 Antibody

Predicted Reactivity: Human

Immunogen: Recombinant human GDF11.

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GDF11

Target: GDF11 (Growth Differentiation Factor 11 (GDF11))

Alternative Name: BMP11

Background:

Synonyms: GDF11, BMP 11, Bone morphogenetic protein 11, GDF 11, Growth differentiation factor 11, Growth/differentiation factor 11, GDF11_HUMAN.

Background: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis, the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.

Gene ID: 10220

UniProt: O95390