IL23R antibody (AA 231-330) (Biotin)

Catalog No. ABIN7091281

The Rabbit Polyclonal anti-IL23R antibody has been validated for WB. It is suitable to detect IL23R in samples from Human.

Quick Overview for IL23R antibody (AA 231-330) (Biotin) (ABIN7091281)

Target: IL23R (Interleukin 23 Receptor (IL23R))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL23R antibody is conjugated to Biotin

Application: Western Blotting (WB)

Product Details anti-IL23R Antibody (Biotin)

Binding Specificity: AA 231-330

Cross-Reactivity: Human

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IL-23R

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for IL23R

Target: IL23R (Interleukin 23 Receptor (IL23R))

Alternative Name: IL-23R

Background:

Synonyms: IL23 Receptor, IL-23R, IL23R, interleukin 23 receptor, IL 23R, IL-23 receptor, IL23R_HUMAN, Interleukin-23 receptor.

Background: Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. Subunit : Heterodimer with IL12RB1. In presence of IL23, the heterodimer forms the IL23 receptor. Interacts with JAK2 and in presence of IL23 with STAT3.

Gene ID: 149233

UniProt: Q5VWK5

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation